iOS 5 is PC-Free!

No longer will you have to take on the cumbersome task of connecting your iDevice to a computer in order to set it up.
iOS 5 presents its users a PC Free experience, which means that devices can be activated wirelessly instantly. As long as your iPhone or iPad has access to a shared Wi-Fi connection, it will sync, update and backup itself with the help of iCloud.
So, for all of you out there that have your parents and/or grandparents constantly hounding you for help with their iDevices, you just received a break.

Source: Apple, MacRumors